Cabergoline ergot Lin is a derivative, is in the nature of DA receptor agonist, its characteristic is strong, long-lasting and selective, and has high affinity with D2 receptors. Blood peak time was 0.5 ~ 4 h, removal of t1/2 about 6 h. The drug is not widely metabolism, along with the urinary and fecal discharge. After giving cabergoline, as a result of DA receptors were stimulated, inhibits prolactin up to 2 weeks.
Mainly used for dopamine agonists, prolactin inhibitors, against Parkinson's agent, etc.
Indications: early and late Parkinson's disease and high blood prolactin
Prolactin type of pituitary adenoma (suitable for bromine hidden pavilion has no effect or take bromine hidden pavilion) in patients with symptoms of a larger
At the university of Pisa in Italy neural science DelDottoP et al reported recently, cabergoline (cabergoline) as a kind of synthetic dopamine agonists may be a high affinity for D2 receptors, thus can be used in early and late the treatment of Parkinson's disease and high blood prolactin.
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