The rapamycin biosynthesis of the rapamycin amount is able by a blazon I polyketide synthase (PKS) in affiliation with a nonribosomal peptide synthetase (NRPS).
The three multienzymes are organized such that the aboriginal four modules of polyketide alternation addendum are in RapA, the afterward six modules for connected addendum are in RapB, and the final four modules to complete the biosynthesis of the beeline polyketide are in RapC.
The domains amenable for the biosynthesis of the beeline polyketide of rapamycin are organized into three multienzymes, RapA, RapB, and RapC, which accommodate a absolute of 14 modules .
more about: Rapamycin
from: Pharmaceutical Ingredients
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