Monday, October 27, 2014

Brief introduction of Cyclosporin D


Chemical Name:   Cyclosporin D
Synonyms:   Val2-cyclosporine;
CAS r:   63775-96-2
 Formula:   C63H113N11O12
Appearance:   White Solid
Melting Point:   147-150°C
Mol. Weight:   1216.64
Storage:   -20°C Freezer
Stability:   No Data Available
Solubility:   Chloroform, Ethyl Aceatate
Category:   Peptides, Pharmaceuticals, Intermediates & Fine Chemicals,
Cyclosporin D is a metabolite of cyclosporin A, an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells.1,2 Cyclosporin D displays about 10% lower immunosuppressant activity than cyclosporine A.3,4 Cyclosporin D has been used as an internal standard for the quantification of cyclosporin A.
from:Acridine Raw Material

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