Sunday, January 17, 2016

Rebamipide: a gastrointestinal careful biologic with pleiotropic activities



Rebamipide, a gastroprotective drug, was developed in Japan and was accurate to be above to cetraxate, the above a lot of assigned biologic of the aforementioned category, in 1989 in the analysis for belly ulcers.

The initially apparent basal mechanisms of action of rebamipide included its action as a prostaglandin inducer and oxygen free-radical scavenger. In addition, several molecules accept been articular as ameliorative targets of rebamipide to explain its pleiotropic pharmacological actions.

In the endure 5 years, several basal and analytic studies accept been performed for anatomic dyspepsia, abiding gastritis, NSAID-induced gastrointestinal injuries, belly abscess afterward abolishment analysis for Helicobacter pylori, belly abscess afterwards endoscopic anaplasty and ulcerative colitis.

more about: Rebamipide

from: Pharmaceutical Ingredients

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