Sunday, August 25, 2013

2-Ethoxybenzamide uses and production methods





Chemical properties :2-Ethoxybenzamide is white or almost white crystalline powder. Melting point 132-134 ℃. Soluble in chloroform, ethanol, acetone, insoluble in water, ether. Almost odorless, tasteless.
Uses: This product is anti-inflammatory drugs, the analgesic effect of salicylic acid amine 2.3 times, 7.5 times as aspirin. For the treatment of headaches, neuralgia, back pain, rheumatic joint pain and colds and so on. Rat oral LD50 of 1160mg/kg.
Uses: used as anti-inflammatory drugs for the treatment of fever, headache, neuralgia, joint pain, arthritis, pain, dysmenorrhea and other illnesses
Production methods: by salicylamide (C7H7NO2, [65-45-2]) by Ethyl derived. The salicylamide, solid sodium hydroxide, ethanol and placed against the pot, enclosed heated to 60-70 ℃, stirred for 30min, cooled to 30 ℃, adding ethyl bromide, and then sealed heating to 80-100 ℃, pressure is not More than 0.2MPa, reaction 3h. Reduced pressure, pH should be 8.5 or more. Filtered hot residue recovered sodium bromide. After most of the ethanol filtrate evaporated, add distilled water precipitated white crystals. Filtered, washed with water until neutral, dried, in o ethoxybenzamide. The yield of about 75%. Dibromoethane may be used instead of ethyl chloroethane reaction, but requires a higher pressure.


More about:2-Ethoxybenzamide suppliers
From:chemical reagent

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