Cleaning Agent ,Metal Cleaning Agent ,Industrial Cleaning Chemical , Metal Surface Treatment
Sunday, December 29, 2013
A brief introduction eptifibatide
Eptifibatide (Integrilin, Millennium Pharmaceuticals, aswell co-promoted by Schering-Plough/Essex), is an antiplatelet biologic of the glycoprotein IIb/IIIa inhibitor class.Eptifibatide is a circadian heptapeptide acquired from a protein begin in the acidity of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the chic of the alleged arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a abbreviate half-life. The biologic is the third inhibitor of GPIIb/IIIa that has begin ample accepting afterwards the specific antibiotic abciximab and the non-peptide tirofiban entered the all-around market.
Integrilin is awash in two strengths, globally: vials absolute 2 mg/ml (20 mg totally) and 0.75 mg/ml (75 mg totally). A third admeasurement is awash in the US: 100 ml vials absolute 2 mg/ml (200 mg totally).
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From:pharmaceutical chemicals
Friday, December 27, 2013
A brief introduction CisAtracurium Besylate
CAS: 96946-42-8
Name: Cisatracurium besylate
English Synonyms: NiMbex; 1 kg - 1.5kg; Cisatracurium; Cis-AttacuriuM; (1R, 1'R, 2R, 2'R) -; Cisatracurium besyla; Cisatrcurium Besylate; cisatracurium besylate; cisatracurium besilate; CisatracuriuM Besilate for Injection
Chinese name: cis-atracurium benzenesulfonamide
Chinese Synonyms: Benzene cis atracurium; benzene sulfonic cisatracurium amine; benzene sulfonamide cis atracurium; cis-benzene sulfonamide atracurium; cis acid atracurium; cis atracurium acid amine; cis-atracurium acid; acid cis-cis atracurium; amine cis atracurium besylate; cis atracurium benzene sulfonate (1R
CBNumber: CB7855410
Formula: C53H72N2O12.2C6H5O3S
Tuesday, December 24, 2013
The main purpose of any Zinc Powder
Any Zinc Powder can be used as a paint of paint and rubber filler. Medicine for making ointment, zinc coating, adhesive plaster on a short for dental materials, such as clove oil zinc oxide cement.
Clove oil zinc oxide cement: also known as a temporary cement paste, oxygen. For deep hole double layer at the bottom of the bottom bearing materials, or bearing single bottom material, a 1 ~ 2 weeks of socket hole, the temporary filling material is used for root canal filling material, join the excipients as periodontal treatment agent.
Doctors often with zinc oxide as clove oil zinc oxide cement.
Used in the treatment of acute itching of skin disease is usually in calamine lotion contains zinc oxide, its use is zinc oxide convergence, protection, and a small amount of corrosion protection.
Zinc is an essential part of rubber and tire industry additive, also used as a natural rubber, synthetic rubber and latex vulcanizing agent and reinforcing agent and colouring agent. If make ordinary zinc oxide nanometer zinc oxide used in rubber, can fully give play to the role of vulcanization, improve the performance of rubber, its amount is only 30% ~ 50% of ordinary zinc oxide.
In the chemical industry, zinc oxide is widely used as a catalyst, desulfurization agent, such as methanol synthesis catalyst, synthetic ammonia as desulfurization agent; Nanometer zinc oxide on the surface of highly active can improve the efficiency of the choice of catalysts and catalytic performance, has wide application potential market.
In the coating industry, zinc oxide besides has the tinting strength and hiding power, and coating of preservatives and FaGuangJi; In addition, the nanometer zinc oxide is excellent ability of uv shielding in the anti-aging coating has more prominent features.
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From:Organic Chemical Compound
Tuesday, December 17, 2013
What is the role Malotilate
Malotilate ACTS on the liver cells, promote the synthesis of RNA, activate the ribosome and improve the ability of protein synthesis, thus activating liver function and inhibit the progress of liver fibrosis. With carbon tetrachloride liver cirrhosis rats model experiment and found this product on serum total protein, albumin, cholinesterase activity and the low of total protein in the liver also had an improved role; Higher serum transaminase activity, serum total cholesterol, low have to restore normal function. This product can also inhibit liver 4 - hydroxy proline content in the increase of collagen fibers (index), pathological histology also prove this product to improve connective tissue hyperplasia and fiber formation. This product of rats caused by carbon tetrachloride and ethyl methionine fatty liver, improve lipid metabolism and reduce the role of liver lipid peroxidation. Applicable to the compensatory cirrhosis when change the improvement of liver function.
Clinical application: suitable for chronic hepatitis, cirrhosis compensatory period and low serum albumin leels are chronic liver disease.
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From:Natural herbal extracts
Thursday, December 12, 2013
The basic information of the phadodendrol
Chinese name: the cuckoo alcohol
English name: Phadodendrol
CAS no. : 59092-94-3
Molecular formula:
Molecular weight: 0
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Tuesday, December 10, 2013
The application of Chondroitin sulfate sodium salt
1, Chondroitin sulfate sodium salt in the medical application main way is as a drug in the treatment of joint diseases, used with glucosamine, with pain, promote cartilage regeneration effect, can fundamentally improve joint problems.
Palliative operation to provide gasket, impact and friction, will water suction proteoglycan molecules inside, make the cartilage thickened, and increasing the amount of intra-articular synovial fluid. Chondroitin is one of the important function as a pipeline, the important of oxygen and nutrients to the joints, joint help remove waste, at the same time, the carbon dioxide and waste. Because there is no blood supply of articular cartilage, so all the oxygen filling, nourishing and lubrication from synovial fluid.
2, chondroitin sulfate for corneal collagen fiber has a protective effect, can promote the growth of the matrix in the fiber, enhance permeability, improve blood circulation, accelerate metabolism, promote permeation fluid absorption and elimination of inflammation; The polyanion has a strong water retention, can improve the moisture of cornea tissue metabolism, has a strong affinity to the cornea, can form a layer of water film on the surface of the cornea, improve the symptoms of dry eye. By promoting the generation of matrix, provides the framework for cell migration, is advantageous to the corneal epithelial cell migration, so as to promote the healing of corneal trauma, exudate absorption and elimination of inflammation.
3, through high-tech processing, can treat neuropathic headache, trigeminal neuralgia, coronary heart disease, angina pectoris, myocardial ischemia, disease of heart head blood-vessel, joint pain, atherosclerosis and hepatitis syndrome, including CS also has anticoagulant and the effect of resisting thrombosis, can also be used to hearing impairment caused by streptomycin and aid in the treatment of liver function damage and aid in the treatment of hyperlipidemia.
4, can be used as in the health care products, food additives, can strengthen the body constitution and antibacterial, beauty, anti-aging, and so on. To improve listening and dry skin. In the body can inhibit intestinal absorption of lipid and glucose in order to achieve the effect reducing weight.
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Wednesday, December 4, 2013
Information about 2-chloroadenosine hemihydrate
CAS: 81012-94-4
Chemical Name: 2-Chloroadenosine hemidydrate
English Synonyms: 2-CADO; 2-CL-ADO; 2-CADO, HEMIHYDRATE; 2-CHLOROADENOSINE HEMIHYDRATE; 2-CHLOROADENOSINE HEMIDYDRATE; 2-Chloroadenosine hemihydrate, 97%; 2-CHLORO-D-ADENOSINE, HEMIHYDRATE; 6-AMINO -2-CHLOROPURINE RIBOSIDE HEMIHYDRATE; 2-Chloroadenosine hemihydrate6-Amino-2-chloropurine riboside
Chinese name: 2 - chloro-adenosine hemihydrate
Chinese Synonyms: 2 - chloro-adenosine hemihydrate; 2 - chloro-adenosine hemihydrate
CBNumber: CB0441353
MF: C10H14ClN5O5
MW: 319.7
MOL File: 81012-94-4.mol
By 2 - chloroadenosine hemihydrate chemical properties
Melting point: 160 ° C (dec.) (lit.)
Storage conditions: -20 ° C
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From:pharmaceutical chemicals
Wednesday, November 20, 2013
What food contains indole - 3 - carbinol
Indole-3-carbinol (C9H9NO) is produced by the breakdown of the glucosinolate glucobrassicin, which can be begin at almost top levels in cruciferous vegetables such as broccoli, cabbage, cauliflower, brussels sprouts, collard greens and kale. I3C is aswell accessible in a comestible supplement. Indole-3-carbinol is the accountable of on-going Biomedical analysis into its accessible anticarcinogenic,antioxidant, and anti-atherogenic effects. Analysis on indole-3-carbinol has been conducted primarily application class animals and able cells. Bound and ambiguous animal studies accept been reported. A contempo analysis of the biomedical analysis abstract begin that "evidence of an changed affiliation amid cruciferous vegetable assimilation and breast or prostate blight in bodies is bound and inconsistent" and "larger randomized controlled trials are needed" to actuate if added indole-3-carbinol has bloom benefits.
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Sunday, November 17, 2013
The appearance of Ferrous Sulfate Heptahydrate characteristics
Ferrous Sulfate Heptahydrate copperas. Green vitriol is a chemical, ferrous sulfate crystals, English name is: ferrous sulfate, for columnar or granular aggregate, irregular block. Green, green with white streaks. The molecular weight of 278.05, pH value of 3, melting point of 64 degrees Celsius, strong thermal decomposition of soluble in water, glycerin, insoluble in ethanol.
Appearance characteristics: crystal structure belongs to monoclinic system. Short columnar crystal, thick plate, fine granular or fibrous, collection show bead block, fiber radial block or leather case, capsule. In all sorts of color of green; When copper is light green blue copperas (copper), water loss, hydroxylation, or oxidation for yellow green, green, yellow to canary yellow, brown spots, red, brown, brown wait for color, transition to a fine iron vitriol melanterite yellow alum or local collection containing limonite); Totally dehydrated pure green vitriol is white. Striation light in color. Fresh crystal transparent, rare; Usually translucent, weathering surface is opaque. Glass, silk luster or earthy luster. Crystal cleavage, fully conchoidal fracture, Weathering is clear see cleavage.
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From:metal materials
Tuesday, November 5, 2013
Dianabol drug instructions
1, after taking Dianabol can have nausea, vomiting, indigestion, diarrhea, etc. Long-term use can cause water sodium retention, edema, jaundice, liver dysfunction, etc.; For female patients can be slightly masculine reaction, such as acne, hirsutism, sound coarsens, clitoral hypertrophy, etc.
2, liver disease, kidney disease, high blood pressure, prostate cancer patients and pregnant women.
3, in order to improve curative effect, should also take a moderate amount of protein, sugar and vitamin, etc.
Oral: adult 10 ~ 30 mg at the beginning of the 1, 2 ~ 3 points served; In remission after to maintain, 5 ~ 10 mg daily, amuse (4 ~ 8 weeks as a course, repeated treatment should be between 1 ~ 2 months. The old man the appropriate dosage reduction. Infants and young children of 0.05 mg/kg daily.
Fitness: twice a day, every time two pieces. (not recommended fitness)
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Dianabol drug instructions
1, after taking Dianabol can have nausea, vomiting, indigestion, diarrhea, etc. Long-term use can cause water sodium retention, edema, jaundice, liver dysfunction, etc.; For female patients can be slightly masculine reaction, such as acne, hirsutism, sound coarsens, clitoral hypertrophy, etc.
2, liver disease, kidney disease, high blood pressure, prostate cancer patients and pregnant women.
3, in order to improve curative effect, should also take a moderate amount of protein, sugar and vitamin, etc.
Oral: adult 10 ~ 30 mg at the beginning of the 1, 2 ~ 3 points served; In remission after to maintain, 5 ~ 10 mg daily, amuse (4 ~ 8 weeks as a course, repeated treatment should be between 1 ~ 2 months. The old man the appropriate dosage reduction. Infants and young children of 0.05 mg/kg daily.
Fitness: twice a day, every time two pieces. (not recommended fitness)
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Sunday, November 3, 2013
Gold powde production methods
Copper zinc powder (commonly known as gold powde) production is of good smelting copper zinc alloy crushing, screening and surface treatment for many times, with paint performance finished product process.
Specific operation process is as follows. In the copper zinc alloy melting furnace under 1100 ℃ within, to strictly control the copper in the process of smelting (3 # copper 99.7% purity, GB466-64) and zinc (zinc - 4 99.5% purity, GB470-64) composition proportion, according to the need to take into the trace of to adjust the hue of alloy aluminum, silicon, nickel, etc. When alloy melting liquid liquid, with compressed air through the nozzle to spray it into powder, alloy powder particles within the water trap condensation, deposition and collected. Collection of atomizing copper zinc powder by screen after washing and drying, into wet sieving machine screening, and then drying dehydration. Dry good copper zinc powder in the ball mill, grinding crushed into the solvent oil and lubricant. Lubricant generally use fatty acids, castor oil and stearic acid salts. Ball mill barrel for stainless steel round the body, the fuselage outside in the cold filter remove solvent filter cake. To form a good scale structure, therefore to annealing treatment of copper and zinc powder, the annealing temperature is 500 ℃, heat preservation, 3 h, then slowly cooled. Again after annealing treatment of copper and zinc powder grinding, fine particles formed a small scales. When using dry grinding, grinding into into stearic acid and its salts as a lubricant, we will strictly control the ratio of grinding ball and filling coefficient, the ball material ratio, dosage of lubricants and other process conditions. When the fineness regulation, with flowing wind will blow out powder collecting container. By dry grinding get more fine pigment particles under 10 microns, need air classification method is used to further classification. After grading of copper and zinc powder in cylinder type polishing machine polishing processing. Machines with small copper ball, glass ball, the copper zinc powder and the right amount of polishing agent, such as castor oil, esters and stearic acid to join in. Polishing temperature in 40 ~ 50 ℃ in general. After polishing to get finished product copper zinc powder paint.
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From:Chemical Reagent
Wednesday, October 30, 2013
CADMIUM BROMIDE TETRAHYDRATE prepared or source
Method one: the hydrobromic acid to the metal cadmium, plus excess bromine water. When most of metal cadmium dissolve, leaching, not soluble cadmium, the filtrate obtained heating evaporation to close to saturation, at 0 degrees Celsius cooling crystallization, crystallization water through recrystallization, isolated is the four cadmium bromide hydrate. Under the condition of vacuum drying, the available water cadmium bromide.
Number two: put metal cadmium in quartz boat, in the heat resistant glass tube filled with dry nitrogen. Under the temperature of 450 ℃, with nitrogen gas through a containing Br2 washing bottle, take Br2 on quartz boat bromination reaction with Cd. Reacting to make 3 g metal cadmium completely, need about 2 h. If you want to improve the reaction temperature to speed the bromination reaction is not desirable, because the higher reaction temperature would have evaporated metal cadmium and products. When the product appeared for * * end of reaction. The CdBr2 in Br2 atmosphere distillation twice, and then melt CdBr2, with pure CO2 removal of excess Br2, cadmium can obtain anhydrous bromide.
Number three: CdBr2 · 4 h2o (see preparation method CdBr2 · 4 h2o) crystals in decompression drying in the dryer, containing potassium hydroxide can get anhydrous cadmium bromide.
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Information about AT3 ELISA Kit
This immunoassay kit allows for the in vitro quantitative assurance of animal anti- thrombin Ⅲ Ⅲ Ⅲ Ⅲ concentrations in serum, claret and added biological fluids.
This appraisal recognizes animal anti- thrombin Ⅲ. No cogent cross-reactivity or arrest was observed.
The microtiter bowl provided in this kit has been pre-coated with thrombin Ⅲ. Standards or samples are again added to the adapted microtiter bowl wells with a biotin-conjugated thrombin Ⅲ and Avidin conjugated to Horseradish Peroxidase (HRP) is added to anniversary microplate able-bodied and incubated. Again a TMB (3,3',5,5' tetramethyl-benzidine) substrate band-aid is added to anniversary well.
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From:Elisa assay kits
Wednesday, October 23, 2013
Information of Lanthanum titanate
Thin films of lanthanum titanate and lithium lanthanum titanate (LLT) accept been developed by diminutive band degradation (ALD). Studies on the advance of lanthanum titanates showed that the lanthanum degradation amount is bargain if the titanium oxide and lanthanum oxide processes are combined, arch to college titanium capacity in the films. The forerunner systems acclimated for degradation of lanthanum titanates were TiCl4 + baptize and La(thd)3 (thd = 2,2,6,6-tetramethyl-3,5-heptanedione) + ozone. Lithium was alien into the actual in adjustment to drop LLT by application lithium tert-butoxide (LiOtBu) and baptize as precursors. The deposited films were analyzed by time-of-flight adaptable backfire apprehension assay (TOF-ERDA), accessory ion accumulation spectrometry (SIMS), X-ray fluorescence (XRF), X-ray reflectivity (XRR) and X-ray diffraction (XRD). TOF-ERDA gave the blur agreement of Li0.32La0.30TiOz at assimilation conditions.
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Information about Drench coccus(NGH) nucleic acid amplification (PCR) quantitative fluorescence detection kit
Neisseria gonorrhoeae (n. gonorrhoeae, Drench coccus) for strict human parasitic bacteria, often found in acute urethritis and vaginitis of purulent secretion of white blood cells, staining similar to meningococcal form. Gonorrhea pathogens is "neisseria gonorrhoeae", that is, commonly known as neisseria gonorrhoeae. This kind of bacteria has self-regulation ability, can gain resistance variation, or at least make the curative effect of drugs, and it is for more and more kinds of antibiotics to develop that immunity. First the penicillin to its failure, again is a tetracycline, ciprofloxacin, and now the cefixime.
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From:Elisa assay kits
Monday, October 21, 2013
Some properties of N - butylpyridinium nitrate description
The body and apparent astriction of the authentic ionic aqueous n-butylpyridinium nitrate ([BuPy]NO3) were bent at temperature ambit from T = (293.15 to 338.15) K. The accessory of thermal expansion, atomic aggregate and filigree activity of [BuPy]NO3 were affected from the beginning ethics of density. The apparent anarchy and enthalpy of [BuPy]NO3 were investigated. The IL advised appearance abundant lower apparent enthalpy and filigree activity in allegory with alloyed salts. The densities and apparent tensions of bifold mixtures of [BuPy]NO3 with baptize accept been abstinent aural the accomplished agreement ambit at T = 298.15 K and atmospheric pressure. Balance molar volumes VE and apparent astriction deviations δγ were again deduced from the beginning after-effects as able-bodied as fractional molar volumes and balance fractional molar volumes. Balance molar volumes accept a abrogating aberration from ideal behavior and the apparent astriction deviations are abrogating over the accomplished compositions range. VE and δγ were activated with acceptable blueprint respectively.
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From:Catalyst chemistry
Wednesday, October 16, 2013
Alpha-Mediterranean anemia gene diagnosis kit (gap-PCR) related presentations
Alpha-Mediterranean anemia gene diagnosis kit (gap-PCR) is capable of α- thalassemia (α- thalassemia ) make a genetic diagnosis kit and its application. The diagnostic kit is to use the principle of double-stranded DNA specific fluorescence real-time fluorescence quantitative PCR (FQ-PCR) combined with melting curve analysis (MC) to detect α- thalassemia various haplotypes can be detected simultaneously without any missing alleles ( ie αα /, including α).
α -thalassemia
1 . Stationary patients are asymptomatic . Normal red blood cell morphology , cord blood at birth Hb Bart's content is 0.01 to 0.02 , but disappeared after 3 months .
2 . Lightweight asymptomatic patients . Mild red blood cell morphology changes, such as size, central light staining , shaped , etc. ; reduce red button cell osmotic fragility ; denatured globin -positive ; HbA2 and HbF levels normal or slightly lower . Children with umbilical cord blood Hb Bart's content was 0.034 ~ 0.140 , at 6 months after birth and disappears completely .
3 . Intermediate , also known as hemoglobin H disease . This type of clinical manifestations are quite different time anemia and anemia of varying severity . Mostly in infancy and then gradually anemia, fatigue, weakness, hepatosplenomegaly , mild jaundice ; older patients may appear similar to severe β thalassemia special face . Combined with respiratory infection or taking oxidizing drugs, antimalarial drugs can induce acute hemolytic anemia aggravated , or even hemolytic crisis .
Laboratory tests : blood and bone marrow changes similar heavy β thalassemia ; erythrocyte osmotic fragility reduction ; denatured globin -positive ; HbA2 and HbF levels to normal. Birth, blood contains about 0. 25Hb Bart's and small HbH; age , HbH gradually replaced Hb Bart's, the amount of from about 0.024 to 0.44 . Inclusion generate test positive.
4 . Heavy known as Hb Bart's hydrops syndrome. Fetus usually within 30 to 40 weeks of miscarriage, stillbirth or death within half an hour after delivery , the fetus showed severe anemia , jaundice , edema , hepatosplenomegaly , ascites, pleural effusion. Placenta huge and brittle.
Laboratory tests : blood mature red blood cell morphological changes such as heavy- β thalassemia , nucleated red blood cells and reticulocytes increased significantly . Almost all hemoglobin Hb Bart's or simultaneously with a small amount of HbH, no HbA, HbA2 and HbF.
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From:Elisa assay kits
Sunday, October 13, 2013
D-Tryptophanol to buy basic information
CAS: 52485-52-6
Product Name: D-Tryptophanol
English Synonyms: D-Tyr-ol; D-Tryptosol; D-Tryptonol; D-TRYTOPHANOL; D-TRYPTOPHANOL; HD-TRYPTOPHANOL; D-(-)-TRYPTOPHANOL; D-Tryptophanol * HCl; REF DUPL: D-Tryptophanol; D-Tryptophanol hydrochloride
Chinese Name: D-Tryptophanol
Chinese Synonyms: D-Tryptophanol
CBNumber: CB3483532
Formula: C11H14N2O
Molecular Weight: 190.24
MOL File: 52485-52-6.mol
D-Tryptophanol chemical properties
Melting Point: 86-89 ° C (lit.)
Specific rotation: -20.5 º (c = 1 in methanol)
Storage conditions: Store at 0-5 ° C
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From:Biochemical Reagent
Friday, October 11, 2013
What is Colloidal gold detection reagent?
Colloidal gold, also known as the gold sol (gold solution), refers to the diameter of the dispersed phase particles between l-150nm gold sol, belonging multiphase heterogeneous system, the color was orange-red to purple. Colloidal gold can be used as markers for immunohistochemistry, the past 10 years has developed into a colloidal gold labeled an important immune markers. Colloidal gold immunoassay in drug detection, and many other areas of biomedical research has been developed, and more and more relevant research fields attention.
Colloidal gold is a commonly used marker technology is based on colloidal gold marker used as a tracer of a novel antigen-antibody immune labeling technique has its unique advantages. In recent years, studies have been widely used in various biological. In clinical use almost all immunoblotting using its mark. While the stream type, electron microscopy, immunohistochemistry, molecular biology as well as cases biochip may be used.
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From:Elisa assay kits
Wednesday, October 9, 2013
Bifidobacterium Brevis understanding of the process
Bifidobacterium Brevis was in 1899 by the French scholar Tissier child nutrition from breast milk isolated from the feces of an anaerobic Gram-positive bacteria, often forked end, hence the name of bifidobacteria.
Bifidobacterium breve - understanding of the process: Since the past two decades the rise of micro-ecology and medical progress of the revolution, so that bifidobacteria increasingly recognized the importance of research. Since bifidobacteria products can be widely used in the world, the masses have recognized its importance. Especially in infants and young children to be able to provide a unique intestinal health protection, effectively reducing infant intestinal infection incidence. The main role of bifidobacteria and widely used, but also for the study of bifidobacteria laid the foundation for the development. After many experts and scholars continue to explore experiments have confirmed that bifidobacteria are the most beneficial intestinal flora, reduction in the number of bifidobacteria are disappearing is "unhealthy" state flag, Bifidobacterium is a barometer of human health. Micro-ecological studies in healthy volunteers found that the number of bacteria in the digestive tract has 100 species, their number reached 100 trillion or more. Human gut bacterial populations to increase as people age varies significantly. Baby 3 to 4 days after birth appears intestinal Bifidobacterium Bifidobacterium infants accounted for approximately 25% of total intestinal bacteria; With increasing age, bifidobacteria gradually reduce or even disappear over 65 years the elderly, the number of bifidobacteria decreased to only 7.9%, while gas production pod Clostridium, E. coli and other bacteria in a significant increase in corruption; into old age full of spoilage bacteria of intestinal bifidobacteria almost disappeared. Spoilage bacteria in the gut break down food ingredients, to produce ammonia, amines, ammonia, sulfide, skatole, indole, phenols, and nitrosamines and other toxic substances, human long-term absorption of these toxins, will accelerate the aging-induced cancer, causing arterial sclerosis, liver disorders and other diseases. Increase the number of bifidobacteria in the body in two ways: "nourishing viable in vitro" and "in vivo growth of viable cells." "In vitro nourishing viable" is the oral administration of a certain number of viable bifidobacteria system.
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From:Lactic acid bacteria
Thursday, August 29, 2013
What is BAM-12P?
BAM-12P Soluble in water. The capacity of this canteen accept been accurately determined. Both the admiration and the canteen accept been siliconized. Do not attack to weight out a abate allocation of the contents. Theoretical conformational assay was acclimated to abstraction the spatial anatomy and conformational backdrop of the bovine adrenal medulla dodecaPeptide BAM-12P (Tyr1-Gly2-Gly3-Phe4-Met5-Arg6-Arg7-Val8-Gly9-Arg10-Pro11-Glu12). Twenty-three low-energy conformations of the BAM-12P courage were apparent to represent the spatial anatomy of the peptide. The changed structural botheration was solved. and constructed analogues of BAM-12P were proposed. the spatial structures of which accord to a set of low-energy potentially physiologically alive conformations of the accustomed dodecapeptide.
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From:polypeptide
Wednesday, August 28, 2013
Lithium aluminium hydride nature and structure
Lithium aluminium hydride is white or off-white crystalline powder, stable in dry air, moist air hydrolysis and cause combustion, soluble in diethyl ether, tetrahydrofuran and the like in an organic solvent; may aldehydes and ketones, acids, anhydrides, esters, quinones, acid chloride other reduced to an alcohol, a primary amine reduction of the nitrile, the halogenated hydrocarbon is a hydrocarbon reduction; but usually not the carbon - carbon double bonds hydrogenated.
Lithium aluminum hydride in a monoclinic crystal structure, space group (English: space group) is P21c, AlH4 tetrahedral ions. Lithium aluminum hydride, Li AlH4 with five adjacent tetrahedron, and with each one of the tetrahedron are bonded hydrogen atoms, with one of the four distance of 1.88-2.00Ã…, and fifth hydrogen distance longer, as 2.16Ã… [2], double pyramidal arrangement. Its cell parameters: a = 4.82, b = 7.81, c = 7.92 Ã…, α = γ = 90 ° and β = 112 °. At high pressure (> 2.2 GPa), the lithium aluminum hydride phase transition occurs, a β-LiAlH4. Right is lithium aluminum hydride cell model, purple ball represents a lithium atom, khaki regular tetrahedron represents AlH4.
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From:chemical metal
Adrenal Peptide E, bovine -related information
Adrenal Peptide E, bovine, a awful potent, 25-amino acerbic adrenal opioid peptide absolute both a [Met]enkephalin at the NH2-terminus and [Leu]enkephalin arrangement at the COOH-terminus, originally abandoned from bovine adrenal medulla [D. L. Kilpatrick, T. Taniguchi, B. N. Jones, A. S. Stern, J. E. Shively, J. Hullihan, S. Kimura, S. Stein, and S. Udenfriend (1981) Proc. Natl. Acad. Sci. USA 78, 3265-3268], is reported. The amalgam was able by the solid-phase adjustment employing the 4-(aminoacyloxymethyl)phenylacetamidomethyl(Pam)-copoly(styrene-1% divinylbenzene) resin. Two constructed strategies (N-indole formyl adequate vs caught tryptophan) were followed and after-effects compared and evaluated. It was bent that peptide E able with aegis of tryptophan (residues 13 and 14) was adopted and gave final artefact that was readily antiseptic by HPLC. The biological action of the constructed actual was begin to be agnate to the appear action of the accustomed compound.
More about:bovine supplier
From:polypeptide
Tuesday, August 27, 2013
Neurotensin synthesis method
Neurotensin is a 13 amino acerbic neuropeptide that is active in the adjustment of luteinizing hormone and prolactin absolution and has cogent alternation with the dopaminergic system. Neurotensin was aboriginal abandoned from extracts of bovine hypothalamus based on its adeptness to could cause a arresting vasodilation in the apparent cutaneous regions of anesthetized rats.
Neurotensin is broadcast throughout the axial afraid system, with accomplished levels in the hypothalamus, amygdala and basis accumbens. It induces a array of effects, including: analgesia, hypothermia and added locomotor activity. It is aswell complex in adjustment of dopamine pathways. In the periphery, neurotensin is begin in endocrine beef of the baby intestine, area it leads to beard and bland beef contraction.
Sequence and biosynthesis:
Neurotensin shares cogent arrangement affinity in its 6 C-terminal amino acerbic residues with several added neuropeptides, including neuromedin N (which is acquired from the aforementioned precursor). This C-terminal arena is amenable for the abounding biological activity, the N-terminal allocation accepting a modulatory role. The neurotensin/neuromedin N forerunner can aswell be candy to aftermath ample 125-138 amino acerbic peptides with the neurotensin or neuromedin N arrangement at their C-terminus. These ample peptides arise to be beneath almighty than their abate counterparts, but are aswell beneath acute to abasement and may represent endogenous, abiding activators in a amount of pathophysiological situations.
The arrangement of bovine neurotensin was bent to be pyroGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH. Neurotensin is actinic as allotment of a 169-170 amino acerbic forerunner protein that aswell contains the accompanying neuropeptide neuromedin N.The peptide coding domains are amid in bike abreast the carboxyl terminal end of the forerunner and are belted and afar by commutual basal amino acerbic (lysine-arginine) processing sites.
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From:polypeptide
Sunday, August 25, 2013
What is Physalaemin?
Physalaemin is a tachykinin peptide acquired from the Physalaemus frog, carefully accompanying to actuality P. Its anatomy was aboriginal elucidated in 1964.
Like all tachykinins, physalaemin is a sialagogue (increases salivation) and a almighty vasodilator with hypotensive effects
Physalaemin (PHY), a non-mammalian tachykinin, binds selectively to neurokinin-1 (NK1) receptor with top affinity. Both the aqueous and lipid-induced conformations of PHY accept been advised application two-dimensional nuclear alluring resonance techniques. These abstracts appearance that in baptize PHY prefers to be in an continued anatomy and that in the attendance of perdeuterated dodecylphosphocholine micelles, a film archetypal system, a circling anatomy is empiric from Pro4 to the C-terminus. Comparison of the structures ofPHYand added NK ligands forth with anatomy action studies appear on these peptide ligands suggests that circling courage structural burden is all-important for the bounden of these NK ligands to the assorted NK receptors. Furthermore, accord in the structures of these ligands suggests that these ligands have to be bounden forth the awful berserk face of the braid that contains the important berserk residues, Phe7, Leu10, and Met11, that are awful conserved in a lot of of the ligands.
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From:polypeptide
2-Ethoxybenzamide uses and production methods
Chemical properties :2-Ethoxybenzamide is white or almost white crystalline powder. Melting point 132-134 ℃. Soluble in chloroform, ethanol, acetone, insoluble in water, ether. Almost odorless, tasteless.
Uses: This product is anti-inflammatory drugs, the analgesic effect of salicylic acid amine 2.3 times, 7.5 times as aspirin. For the treatment of headaches, neuralgia, back pain, rheumatic joint pain and colds and so on. Rat oral LD50 of 1160mg/kg.
Uses: used as anti-inflammatory drugs for the treatment of fever, headache, neuralgia, joint pain, arthritis, pain, dysmenorrhea and other illnesses
Production methods: by salicylamide (C7H7NO2, [65-45-2]) by Ethyl derived. The salicylamide, solid sodium hydroxide, ethanol and placed against the pot, enclosed heated to 60-70 ℃, stirred for 30min, cooled to 30 ℃, adding ethyl bromide, and then sealed heating to 80-100 ℃, pressure is not More than 0.2MPa, reaction 3h. Reduced pressure, pH should be 8.5 or more. Filtered hot residue recovered sodium bromide. After most of the ethanol filtrate evaporated, add distilled water precipitated white crystals. Filtered, washed with water until neutral, dried, in o ethoxybenzamide. The yield of about 75%. Dibromoethane may be used instead of ethyl chloroethane reaction, but requires a higher pressure.
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From:chemical reagent
Friday, August 23, 2013
New peptide Phyllomedusin
Phyllomedusin is a new peptide of the tachykinin family, Phyllomedusin acerb affects the salivary glands, breach ducts, intestines, and bowels, and Phyllomedusin contributed to the agitated purging. Tachykinins are alive peptides which accelerate neurons, arm-twist behavioral responses, are almighty vasodilators and secretagogues, and Phyllomedusin arrangement (directly or indirectly) abounding bland muscles. Phyllomedusin is Secreted protein and Expressed by the derma glands. Phyllomedusin Belongs to the tachykinin family.
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From:polypeptide
Wednesday, August 21, 2013
Buccalin basic information
CAS Number: 116786-35-7
English name: BUCCALIN
English Synonyms: BUCCALIN; GMDSLAFSGGL-NH2; GLY-MET-ASP-SER-LEU-ALA-PHE-SER-GLY-GLY-LEU-NH2; H-GLY-MET-ASP-SER-LEU-ALA-PHE-SER -GLY-GLY-LEU-NH2
CBNumber: CB4199315
Formula: C45H72N12O15S
MW: 1053.19
MOL File: 116786-35-7.mol
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From:Natural Food Colors
Tuesday, August 13, 2013
Titanium Dioxide some explanations
Titanium dioxide, chemical formula TiO2, commonly known as titanium dioxide, used photocatalyst, cosmetics, can rely on UV disinfection and sterilization, are now being extensively developed, will have the opportunity to become the new industry. Rutile titanium dioxide can be extracted with an acid decomposition, or by the decomposition of titanium tetrachloride. Titania stable, for a large number of white pigment in paint, it has good covering power, and white lead are similar, but not as white lead will be black; it also has the same durability zinc white. Titanium dioxide is also used as a matting agent of enamel, can produce a very bright, hard and acid-resistant enamel overlay.
Titanium dioxide (chemical formula: TiO2), a white solid or powder form amphoteric oxide, is the best white pigment, commonly known as titanium dioxide. Strong adhesion of titanium dioxide, a chemical change is not easy, is always white. Especially valuable is nontoxic titanium dioxide. Its high melting point, is used to manufacture fire-resistant glass, glaze, enamel, clay, utensils and other high-temperature experiments.
Rutile titanium dioxide can be extracted with an acid decomposition, or by the decomposition of titanium tetrachloride. Titania stable, for a large number of white pigment in paint, it has good covering power, and white lead are similar, but not as white lead will be black; it also has the same durability zinc white. Titanium dioxide is also used as a matting agent of enamel, can produce a very bright, hard and acid-resistant enamel overlay.
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From:Natural Food Colors
Monday, August 12, 2013
Marigold Oleoresin basic information
Concept: Marigold Oleoresin is a marigold particles through subcritical obtained after low temperature extraction semifluid paste.
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Uses: mainly used for lutein extract from the processing of natural lutein or crystal. As food additives, colorants, feed additives.
Processing technology: Currently, the market sold mainly from marigold flower extract lutein deep processing, processing is as follows:
Marigold flowers harvest - hydrolysis - dehydration - drying - granulation - low leaching - lutein extract - packaging.
Lutein extract low temperature extraction process is subcritical temperature leaching (Regent Oil Engineering Co., Ltd. Anyang patented technology), obtained by the method subcritical cryogenic extraction of active ingredients lutein extract indicators relative yield of trans-lutein higher, can effectively reduce the waste of resources should be promoted processing methods.
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From:Natural Food Colors
Wednesday, August 7, 2013
Fucoxanthin has a slimming effect
Fucoxanthin also known as pheophytin for brown algae diatoms, golden algae and green algae contained yellow pigment in photosynthesis photochemical system Ⅱ. Separation may be a red-brown crystals, which is a leaf zeaxanthin, is to render a brown brown algae substance brown algae can be said specific dye, scattered sometimes appeared in diatoms and other algae . Sometimes with fucoxanthin (phycophaein also translated pheophytin) confused, but fucoxanthin (phycophaein) that is unique to a water-soluble alginate dye class, and seems to be a hypothetical substance seems to refer to death in plants After the class contained in the brown algae as a phenolic substance is oxidized to form a brown substance, they are essentially different.
Weight loss: weight loss, obviously, fucoxanthin are two ways to eliminate fat accumulation. Fucoxanthin can activate called UCP1 protein that can promote fat decomposition. It also stimulates the liver to produce cholesterol levels DHA.
Japan's Hokkaido University researchers confirmed that fucoxanthin - a brownish algae pigment substance - will become a panacea for weight loss. Researchers conducted experiments on mice found that by regularly adding fucoxanthin containing food additives, 5-10% weight loss in mice. Scientists have only a total of over two hundred mice were studied. In the experiment, scientists found that fucoxanthin are two ways to eliminate fat accumulation. Fucoxanthin can activate called UCP1 protein that can promote fat decomposition. It also stimulates the liver to produce cholesterol levels DHA. Scientists have also confirmed that the use of a concentrated fucoxanthin animal food additives do not cause any side effects or other addiction.
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From:Natural Food Colors
Monday, August 5, 2013
Turmeric yellow water soluble Profile
Turmeric Turmeric is Zingiberaceae species, in some Asian countries called turmeric or kunyit. Its roots are ground into a deep yellow curry powder spices is one major, also used in Southeast Asia dishes tasted bitter and spicy, a little earthy. Main ingredient curcumin (curcumin) has some health effects, so turmeric also appeared in the Han medicine timber.
Function of taste: turmeric spicy, bitter, warm. Main function is expelling gas line.
Concurrent turmeric expelling blood and qi stagnation, into two by the liver and spleen, liver and spleen two good break through the blood stasis and qi nodal function blood stasis, qi pain.
Pharmacology: According to recent research reports, turmeric hepatitis virus inhibition, to improve the role of parenchymal lesions.
Turmeric excitatory role of the uterus, uterine contractions paroxysmal; can promote bile secretion in anesthetized dogs, but are less effective and lasting.
Chinese medicine Turmeric traits: Herbal Turmeric irregular oval, cylindrical or fusiform, often curved, some with short forked branches, length 2 ~ 5cm, diameter of 1 ~ 3cm. Surface deep yellow, rough, wrinkled texture and obvious links, and a round branching and fibrous scar marks. Quality solid and difficult to break, the cross section brownish yellow to golden yellow, horn-like, wax-like luster, ringed evident within the cortex, vascular bundles scattered punctate. Specific gas smell, bitter, acrid.
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From:natural food colors
Thursday, August 1, 2013
Albuterol sulfate use and some considerations
Purpose:
Albuterol sulfate indications: bronchial asthma, asthmatic bronchitis and emphysema.
Role: Selective bronchial smooth muscle excitement on β2-receptors, the bronchial smooth muscle relaxation, thereby lifting the bronchial smooth muscle spasm. Adverse reactions: mainly on the heart and central nervous system stimulant, such as headache, dizziness, insomnia, occasional muscle and finger tremor, palpitations, blood pressure fluctuations. Long-term use can produce drug resistance, may aggravate asthma.
Note:
Pregnancy Category C. Cardiovascular dysfunction, hypertension, hyperthyroidism, diabetes and pregnancy in patients with caution. Increased use of inhaled short-acting b2-agonists to control symptoms, showing attenuation of asthma control, if this happens, you should re-evaluate the patient's treatment. Control of asthma sudden and gradual decay, the patient's life may be in danger, began to implement or increase should be considered corticosteroid treatment. If the patient has this crisis, should exercise the greatest tidal volume of daily monitoring. Home treatment of patients receiving the goods should note that if the soothing effect or duration than usual reduced, it should not increase the dose or administration of their own times.
For known to use large doses of other sympathomimetic drugs patients should be careful.
Patients suffering from thyrotoxicosis should be matched with caution b2-agonist therapy (mainly used for injection and aerosol).
There are potentially serious hypokalemia disease, if the patient is suffering from acute severe asthma, should pay particular attention this adverse effect because while taking xanthine inducing drugs, steroids and diuretics, and the emergence of hypoxia will involve hypokalemia cases were transferred, in case of such situation, you must be careful monitoring of serum potassium levels.
On pregnancy and lactation: women during pregnancy should not inhale the drug, if diagnosed by a doctor that the use of this drug in pregnant women may result in benefits outweigh the risk to the fetus, may consider using this medicine. Avandia women, postpartum bleeding emulsion may have the goods hormone drugs, so unless the expected benefits outweigh the possible hazards arising from, or for women to breastfeed infants should not inhale the drug, has yet to prove that breast milk whether the product in newborn babies harmful.
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From:Chem pharma
Wednesday, July 31, 2013
Glibenclamide in ectopic pregnancy Applications
Glibenclamide by increasing insulin levels, or the portal vein directly to the liver, inhibition of hepatic glycogenolysis and gluconeogenesis, reduced hepatic glucose production and output; oral absorption, high protein binding, was 95% after oral administration of 2 to 5 hour plasma concentration peak, continued for 24 hours. T1 / 2 was 10 hours. Metabolized in the liver by the hepatic and renal excretion of approximately 50%.
In ectopic pregnancy in the application:
Ectopic pregnancy is a common gynecological acute abdomen, the incidence increased significantly in recent years, but increased in patients without a child. With the fast and sensitive β-hCG detection technology to carry out, high-resolution B-application, make the most of unruptured ectopic pregnancy prior to the diagnosis, conservative treatment for drug provided the conditions [1], on the need to retain reproductive function in patients, choice of drugs and the best treatment is a question worth exploring. Conservative treatment of ectopic pregnancy has made great progress, has become a major means of treatment [2], and its advantage is that it not only kills the embryo tissue, without destroying the fallopian tubes, thereby maintaining tubal patency. At present, domestic and conservative about ectopic pregnancy reported that the majority of drug treatment used methotrexate (MTX).
However, methotrexate damage to the body's response to chemotherapy great many side effects. Mifepristone inception, gradually being used in the treatment of ectopic pregnancy, less the number of days for menopause, progesterone levels are relatively lower, mifepristone anti-pregnancy better. In this paper, 50 cases of ectopic pregnancy in patients with methotrexate (methotrexate, MTX) as the control, observation of mifepristone (mifepristone, Mif) the efficacy of treatment of ectopic pregnancy, to explore a safe, effective, convenient, less side effects of treatment.
Object of study and grouping May 1999 ~ October 2003 ectopic pregnancy diagnosed 50 patients hospitalized, the youngest 20 years old, maximum 41 years, mean 27 years, menopause time 38 to 65 days. Diagnosis is based on history, gynecological examination, serum β-hCG and B-ultrasound, except by curettage uterine pregnancy. Medication for: (a) unruptured ectopic pregnancy or tubal pregnancy rupture, but less bleeding; (2) B-ultrasound tubal pregnancy mass diameter 6000U / L and conservative treatment in patients with medication requirements, no taboo mifepristone licenser. (6) liver and kidney functions were normal, peripheral WBC, RBC, PLT were within normal range.
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From:Chem pharma
Monday, July 29, 2013
What is Cremophor EL?
Traits: according to the number of ethylene oxide molecularcondensation of gradually increased, from the thin oil graduallybecome sticky and even become waxy semisolid.
Use: a nonionic surfactant. Mainly used in aqueous phase emulsifier. Mainly used as pesticide emulsifier and printing pigment dispersing agent.
Preparation or source: from castor oil 1 molar and ethylene oxide20 to 40 moles of shrinkage and.
Product Application:Cremophor EL is the registered brand of BASF Corp. for its adaptation of polyethoxylated brush oil. It is able by reacting 35 moles of ethylene oxide with anniversary birthmark of brush oil. The consistent artefact is a admixture (CAS amount 61791-12-6): the above basic is the actual in which the hydroxyl groups of the brush oil triglyceride accept ethoxylated with ethylene oxide to anatomy polyethylene glycol ethers.Minor apparatus are the polyethyelene glycol esters of ricinoleic acid, polyethyelene glycols and polyethyelene glycol ethers of glycerol.It is acclimated as a bread-and-butter and emulsifier for the water-insoluble drugs or added fat-soluble drugs.It is acclimated in doughy and aqueous formulations.
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From:Chem pharma
Friday, July 26, 2013
Pharmacological effects on Clemastine Fumarate introduction
Clemastine fumarate is a white or almost white crystalline powder, odorless, slightly bitter taste. Clemastine fumarate (Clemastine Fumarate) is a Swiss Sandoz (Sandoz) company in the 1960s successfully developed antihistamines. Thereafter, in the United States, Japan, Germany, put on the market. This product is a typical, representative of the second generation H1 receptor antagonists, histamine clinically for the treatment cited by the various allergic diseases, is currently the world's best recognized antihistamines world.
Pharmacological effects:
Clemastine fumarate tablets of Shandong Institute of Pharmaceutical Industry in China developed the first of the original four new drugs, new drug to obtain a certificate, also received three years of administrative protection.
After forty years of clinical practice of foreign and domestic clinical validation summary, clemastine fumarate is a fast-acting, long-lasting, efficient, safe and reliable antihistamines. Clemastine fumarate tablets pharmacokinetics in humans showed that the oral absorption fast, effective after 30 minutes, quickly relieve symptoms, one hour after the plasma concentration reached the highest value compared with similar antihistamines such as astemizole, chlorine loratadine contrast, this product is the fastest effective. Its anti-histamine effect sustainable 12 hours, anti-histamine effect 10 times stronger than chlorpheniramine, drowsiness side effects (central role) is minimal. Treatment of allergic rhinitis total effective rate was 98%, the treatment of chronic urticaria urticaria cure rate 61.3%. Clemastine is not only basophils and lung tissue by the release of histamine antagonism, but at high concentrations toxic to cells also have a certain antagonism, drug on allergic diseases has many therapeutic effects. Mainly used in clinical allergic rhinitis, urticaria, eczema and other allergic dermatitis.
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From:Chem pharma
Thursday, July 25, 2013
For the purpose of PVP K90
Purpose:
PVP (PVP K90) as a synthetic water-soluble polymer, a water-soluble polymer of the general nature of the protective colloid effect, film, adhesion, moisture, solubilization, or cohesion, but its most characteristics, and thus subject to people's attention is its excellent solubility and physiological compatibility. In synthetic polymers such as PVP both soluble in water, but soluble in most organic solvents, low toxicity, good physiological compatibility and rare, especially in the pharmaceutical, food, cosmetics these closely related with people's health field, along with its lower prices of raw materials butyrolactone, will demonstrate its good prospects for development. The following is a detailed description of its application areas:
Medicine & Health
PVP has excellent physical inertia, not involved in human metabolism, but also has excellent biocompatibility, skin, mucous membranes, eyes, which do not form any stimulation. From a biological point of view, PVP molecular structure of the protein features a simple model of similar kind of structure, even its water-soluble to some small molecules with the ability of some proteins and can be ammonium sulfate precipitant, trichloroacetic acid, tannic acids and other characteristics of the precipitated proteins and also compatible. So that the PVP is widely used as materials of pharmaceutical preparations, specific applications as follows: ① ② for the preparation of a binder as precipitant ③ Injection cosolvents or crystal formation preventing agent or a coating film-forming agent ④ ⑤ delay, release agents prolong the drug controlled release duration of action of drugs artificial vitreous and cornea ⑥ ⑦ ⑧ PVP iodine surgical dressings disinfectant. In addition, PVP can also be used as a colorant and a X-ray contrast agent; for tablets, granules, liquid drugs and other forms, with detoxification, bleeding, increased concentration of dissolved prevent peritoneal adhesions, to promote sedimentation and so on.
Food processing
PVP itself is not carcinogenic, good food safety, to the specific polyphenol compounds (such as tannins) form a complex in the food processing primarily as beer, fruit juice, wine and other foods clarifying agents and stabilizers.
Daily cosmetics
In PVP, consumption structure, the cosmetics industry in developed countries accounted for 30% to 50%, China accounted for 70% to 80%. Because PVP has a very low toxicity and physiologically inert, it skin, eye irritation, in the field of medicine has a long record of use, so it is safe for cosmetics. In daily use cosmetics, PVP and copolymers with good dispersion and film-forming properties, PVP in the emulsion has a protective colloid can be used for fatty and non-fatty cream that is used for setting lotions, hair sprays and Mount silk styling agent, hair sunscreen agents, shampoo foam stabilizer agents for hair styling wave dispersing agent and the affinity agent. In cream, sunscreen, depilatories adding PVP, can enhance wetting and lubricating effect.
Detergent field
PVP has anti-soil redeposition performance for the preparation of transparent liquid or heavy dirt detergent, the detergent is added PVP has a good anti-turn color effect, and can enhance the washing ability, wash fabric of synthetic detergent to prevent skin irritation, especially for fibers, this performance than carboxymethyl cellulose (CMC) type detergent more prominent. PVP complex with borax, phenol disinfectant cleaner formulation as the active ingredient. PVP with hydrogen peroxide in the solid detergent compound, a bleaching effect of killing bacteria.
Textile
PVP and many organic dyes have a good affinity, which can be used with polyacrylonitrile, esters, nylon, and hydrophobic fibrous materials, synthetic fibers, and to improve dyeability and hydrophilicity.
Paint and color
PVP coated with paint, paint transparent film without affecting the color, to improve the coating and paint gloss and dispersibility, improved thermal stability and can improve the dispersibility of the ink and other inks.
Polymer Technology
Polyvinyl pyrrolidone as a polymer surfactant dispersion in different systems, can be used as dispersants, emulsifiers, thickeners, leveling agents, particle size adjusting agents, anti-redeposition agents, flocculants, solvent and washing agent.
Other aspects
PVP can be used as a gelling agent tertiary oil recovery, enhanced oil oil recovery rate. As a photosensitive material is latex additive helps to reduce the developed image and enhanced degree of coverage. Polymerization process the polymer as a thickening agent, a dispersion stabilizer and adhesion regulating agent. In the paper industry as a dispersing agent in the gasification of acrylamide as a cocatalyst. PVP in the membrane, light-cured resin, laser disc, drag-reducing coatings, building materials, steel and electroplating and other fields are also rising.
More about:PVP K90 supplier
From:Chem pharma
Wednesday, July 24, 2013
Kollidon 25 product applications
Product name:Kollidon 25
Product Application:Kollidon 25 is a average atomic weight (W28 ,000-34, 000)product.Kollidon 25 is mainly acclimated in tablets, capsules and granules of the adhesive; articulate abeyance stabilizer, film-forming agent, blush area dispersant, thickeners, agitator stabilizers and it is aswell acclimated to advance the bioavailability of baffling drugs.
The acrid Kollidon grades are decidedly acceptable for wet granulation processes in absorption of 1 to 5%, or with band-aid of adhesive or bread-and-butter (e.g. water). Kollidon® 25 and Kollidon® 30 can aswell be acclimated in tabletting processes at concentrations commensurable to absorption in wet granulation processes. All varieties of acrid Kollidon (Kollidon®) are aswell acclimated in ophthalmic preparations. Kollidon® 17 PF, Kollidon® 25 and Kollidon® 30 formulations are frequently acclimated in eye drops, and Kollidon® 90F is adopted in solutions for acquaintance lenses. A different affection of povidone is their adeptness to anatomy complexes with the alive substances, so that they can be an able apparatus to advance the dissolution of abounding drugs.
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From:Chem pharma
Sunday, July 21, 2013
What is Cremophor ELP?
Abstract:
Cremophor ELP is a conception car acclimated for assorted poorly-water acrid drugs, including the anticancer abettor paclitaxel (Taxol). In adverse to beforehand reports, CrEL is not an apathetic vehicle, but exerts a ambit of biological effects, some of which accept important analytic implications. Its use has been associated with astringent anaphylactoid hypersensitivity reactions, hyperlipidaemia, aberrant lipoprotein patterns, accession of erythrocytes and borderline neuropathy. The pharmacokinetic behaviour of CrEL is dose-independent, although its approval is awful afflicted by continuance of the infusion. This is decidedly important back CrEL can affect the disposition of assorted drugs by alteration the absolved biologic absorption through micellar encapsulation. In addition, it has been apparent that CrEL, as an basic basic of paclitaxel chemotherapy, modifies the toxicity contour of assertive anticancer agents accustomed concomitantly, by mechanisms added than active interference. A bright compassionate of the biological and pharmacological role of CrEL is capital to advice oncologists abstain side-effects associated with the use of paclitaxel or added agents application this vehicle. With the present development of assorted new anticancer agents, it is recommended that another conception approaches should be pursued to acquiesce a bigger ascendancy of the toxicity of the analysis and the pharmacological interactions accompanying to the use of CrEL.
Chemical nature:
Like Cremophor ELP, Cremophor ELP is a nonionic solubiliser fabricated by reactingcastor oil with ethylene oxide in a molar arrangement of 1 : 35. This is ollowed by apurifcation process
PharmacopÅ“ias:Cremophor ELP meets the requirements of the accepted Ph.Eur. Monograph,“Macrogolglycerol Ricinoleate”. It aswell conorms to the latest monograph,“Polyoxyl 35 Castor Oil”.
Solubility:Cremophor ELP forms bright solutions in baptize and aswell dissolves in a widerange of amoebic solvents, such as ethanol, n-propanol, isopropanol, ethyl ace-tate, chloroorm, carbon tetrachloride, trichloroethylene, toluene and xylene.
More about:Cremophor ELP prices
From:Chem pharma
Wednesday, July 17, 2013
The Kollicoat SR 30 D Products
Abstract:A anew accessible polyvinylacetate aqueous dispersion, Kollicoat SR 30 D, was evaluated with account to its adeptness to attune the in vitro absolution of a awful water-soluble archetypal admixture (diphenhydramine hydrochloride) from nonpareil-based systems. Kollicoat SR 30D premixed with a called plasticizer (10% wt/wt propylene glycol, 2.5% triethyl citrate, or 2.5% dibutyl sebacate), talc, and red #30 basin dye was coated assimilate the biologic chaplet in an Aeromatic Strea I fluid-bed drier with a Wurster admit application basal spray. With propylene glycol as the plasticizer, increases in polymer blanket akin backward biologic absolution from chaplet in a stepwise appearance forth with credible permeability, advertence a constant absolution mechanism. Stability studies at 40 degrees C/75% RH appear bit-by-bit decreases in dissolution rate, and added abating studies added accepted the assurance of absolution kinetics on abating condition. Furthermore, the blazon of plasticizer was begin to play a key role. Unplasticized formulations apparent the fastest dissolution, followed by formulations plasticized with triethyl citrate, propylene glycol, and dibutyl sebacate. All 4 formulations (unplasticized and plasticized), nevertheless, appear a apparent aberration amid uncured and convalescent dissolution profiles. Kollicoat SR 30D has, thereby, been approved to finer arrest biologic absolution from nonpareil-based systems. However, called plasticizer blazon and consecutive abating action play important roles in authoritative biologic absolution from such a system.
The Kollicoat SR 30D chargeless filmwas able by casting technique. The filmtension was activated by the self-made filmtension analysis device. The furnishings of plasticizer and porogen on the compactness acreage and moisture-penetrability of the filmwere investigated. The after-effects adumbrated that the addendum arrangement and moisture-penetrability of the filmwere signifcantly added with the accretion of plasticizer (triethyl citrate, TEM). Three porogens [polyethylene glycol (PEG) 6000, polyvidone (PVP) K30 and hydroxy propyl methyl artificial (HPMC) E5] could advance the moisture-permeability, but had no significantinfluenceson the addendum ratio. Added tests showed that the bulk of PEG had no cogent influences on addendum arrangement and moisture-penetrability of the blur with% TEM as plasticizer.
More about:Kollicoat SR 30 D supplier
From: Chem pharma
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